ncRNA name | hsa-miR-18a |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines Y79, RBL30 and RB355 |
Methods | qPCR, Western blot, immunofluorescence staining, cell viability assay, BrdU incorporation assay, CAM assay, luciferase reporter assay |
Expression pattern | associated |
Functional description | TFF1-induced apoptosis is mediated through transcriptional activity of p53 with concurrently downregulated miR-18a expression. |
PubMed ID | 28481041 |
Year | 2017 |
Title | Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulation. |
Drug-related ncRNA | NO |
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